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Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism

Genetic risk variants and transcriptional expression changes in autism spectrum disorder (ASD) were widely investigated, but their causal relationship remains largely unknown. Circular RNAs (circRNAs) are abundant in brain and often serve as upstream regulators of mRNAs. By integrating RNA-sequencin...

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Detalles Bibliográficos
Autores principales: Mai, Te-Lun, Chen, Chia-Ying, Chen, Yu-Chen, Chiang, Tai-Wei, Chuang, Trees-Juen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734057/
https://www.ncbi.nlm.nih.gov/pubmed/35962193
http://dx.doi.org/10.1038/s41380-022-01714-4