Cargando…

Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism

Genetic risk variants and transcriptional expression changes in autism spectrum disorder (ASD) were widely investigated, but their causal relationship remains largely unknown. Circular RNAs (circRNAs) are abundant in brain and often serve as upstream regulators of mRNAs. By integrating RNA-sequencin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mai, Te-Lun, Chen, Chia-Ying, Chen, Yu-Chen, Chiang, Tai-Wei, Chuang, Trees-Juen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734057/ https://www.ncbi.nlm.nih.gov/pubmed/35962193 http://dx.doi.org/10.1038/s41380-022-01714-4

Ejemplares similares

CircMiMi: a stand-alone software for constructing circular RNA-microRNA-mRNA interactions across species
por: Chiang, Tai-Wei, et al.
Publicado: (2022)

Assessing the impacts of various factors on circular RNA reliability
por: Chuang, Trees-Juen, et al.
Publicado: (2023)

Genome-wide, integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autism
por: Chen, Yen-Ju, et al.
Publicado: (2020)

NCLcomparator: systematically post-screening non-co-linear transcripts (circular, trans-spliced, or fusion RNAs) identified from various detectors
por: Chen, Chia-Ying, et al.
Publicado: (2019)

NCLscan: accurate identification of non-co-linear transcripts (fusion, trans-splicing and circular RNA) with a good balance between sensitivity and precision
por: Chuang, Trees-Juen, et al.
Publicado: (2016)

Biogenesis, identification, and function of exonic circular RNAs
por: Chen, Iju, et al.
Publicado: (2015)

Comment on "A comprehensive overview and evaluation of circular RNA detection tools"
por: Chen, Chia-Ying, et al.
Publicado: (2019)

A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations
por: Mai, Te-Lun, et al.
Publicado: (2019)

An Evolutionary Landscape of A-to-I RNA Editome across Metazoan Species
por: Hung, Li-Yuan, et al.
Publicado: (2017)

Detecting intragenic trans-splicing events from non-co-linearly spliced junctions by hybrid sequencing
por: Chen, Yu-Chen, et al.
Publicado: (2023)

Impacts of Pretranscriptional DNA Methylation, Transcriptional Transcription Factor, and Posttranscriptional microRNA Regulations on Protein Evolutionary Rate
por: Chuang, Trees-Juen, et al.
Publicado: (2014)

Integrative transcriptome sequencing reveals extensive alternative trans-splicing and cis-backsplicing in human cells
por: Chuang, Trees-Juen, et al.
Publicado: (2018)

The Impact of Trans-Regulation on the Evolutionary Rates of Metazoan Proteins
por: Chen, Yi-Ching, et al.
Publicado: (2013)

Detection of circular RNA expression and related quantitative trait loci in the human dorsolateral prefrontal cortex
por: Liu, Zelin, et al.
Publicado: (2019)

Controlling for false positive findings of trans-hubs in expression quantitative trait loci mapping
por: Peng, Jie, et al.
Publicado: (2007)

Assessment of imprinting- and genetic variation-dependent monoallelic expression using reciprocal allele descendants between human family trios
por: Chuang, Trees-Juen, et al.
Publicado: (2017)

Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci
por: Davis, Lea K, et al.
Publicado: (2012)

Different alternative splicing patterns are subject to opposite selection pressure for protein reading frame preservation
por: Chen, Feng-Chi, et al.
Publicado: (2007)

The effects of multiple features of alternatively spliced exons on the K(A)/K(S )ratio test
por: Chen, Feng-Chi, et al.
Publicado: (2006)

DNA Methylation is Associated with an Increased Level of Conservation at Nondegenerate Nucleotides in Mammals
por: Chuang, Trees-Juen, et al.
Publicado: (2014)

Is an observed non-co-linear RNA product spliced in trans, in cis or just in vitro?
por: Yu, Chun-Ying, et al.
Publicado: (2014)

Construction of ddRADseq-Based High-Density Genetic Map and Identification of Quantitative Trait Loci for Trans-resveratrol Content in Peanut Seeds
por: Luo, Huaiyong, et al.
Publicado: (2021)

Genetic complexity at expression quantitative trait loci
por: Cantor, Rita M., et al.
Publicado: (2016)

Quantitative Trait Loci Mapping
por: Grisel, Judith E., et al.
Publicado: (1995)

Purifying selection shapes the coincident SNP distribution of primate coding sequences
por: Chen, Chia-Ying, et al.
Publicado: (2016)

ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci
por: Stacey, David, et al.
Publicado: (2019)

Lead Modulates trans- and cis-Expression Quantitative Trait Loci (eQTLs) in Drosophila melanogaster Heads
por: Qu, Wen, et al.
Publicado: (2018)

INDELSCAN: a web server for comparative identification of species-specific and non-species-specific insertion/deletion events
por: Chen, Feng-Chi, et al.
Publicado: (2007)

CNVVdb: a database of copy number variations across vertebrate genomes
por: Chen, Feng-Chi, et al.
Publicado: (2009)

Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency
por: Wu, Chan-Shuo, et al.
Publicado: (2014)

Genetic Complexity and Quantitative Trait Loci Mapping of Yeast Morphological Traits
por: Nogami, Satoru, et al.
Publicado: (2007)

Mapping epistatic quantitative trait loci
por: Laurie, Cecelia, et al.
Publicado: (2014)

Identification and evolutionary analysis of novel exons and alternative splicing events using cross-species EST-to-genome comparisons in human, mouse and rat
por: Chen, Feng-Chi, et al.
Publicado: (2006)

Quantitative trait loci mapping of panicle traits in rice
por: Jia, Baoyan, et al.
Publicado: (2019)

Genetic Mapping of Quantitative Trait Loci Underlying Flowering Time in Chrysanthemum (Chrysanthemum morifolium)
por: Zhang, Fei, et al.
Publicado: (2013)

Identification of Quantitative Trait Loci for Component Traits of Flowering Capacity Across Temperature in Petunia
por: Chen, QiuXia C., et al.
Publicado: (2019)

QTG-Finder: A Machine-Learning Based Algorithm To Prioritize Causal Genes of Quantitative Trait Loci in Arabidopsis and Rice
por: Lin, Fan, et al.
Publicado: (2019)

Quantitative trait loci for fertility traits in Finnish Ayrshire cattle
por: Schulman, Nina F, et al.
Publicado: (2008)

Detection of quantitative trait loci for carcass composition traits in pigs
por: Milan, Denis, et al.
Publicado: (2002)

Single cell expression quantitative trait loci and complex traits
por: Petretto, Enrico
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_v9t9d6dr8id77ja09q392p6ud1