Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes

The midbrain is an extensively studied brain region in schizophrenia, in view of its reported dopamine pathophysiology and neuroimmune changes associated with this disease. Besides the dopaminergic system, the midbrain contains other cell types that may be involved in schizophrenia pathophysiology....

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Detalles Bibliográficos
Autores principales: Puvogel, Sofía, Alsema, Astrid, Kracht, Laura, Webster, Maree J., Weickert, Cynthia Shannon, Sommer, Iris E. C., Eggen, Bart J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734060/
https://www.ncbi.nlm.nih.gov/pubmed/36192459
http://dx.doi.org/10.1038/s41380-022-01796-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734060/
https://www.ncbi.nlm.nih.gov/pubmed/36192459
http://dx.doi.org/10.1038/s41380-022-01796-0

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