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Regulating voltage-gated ion channels with nanobodies

In this work, Morgenstern and colleagues describe an approach involving functionalized nanobodies which decrease the activity of voltage-gated Ca(2+) channels associated with β(1) subunits and promote their removal from the surface membrane of neurons and muscle.

Detalles Bibliográficos
Autores principales: Manning, Declan, Santana, L. Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734093/
https://www.ncbi.nlm.nih.gov/pubmed/36494383
http://dx.doi.org/10.1038/s41467-022-35027-5