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Regulating voltage-gated ion channels with nanobodies
In this work, Morgenstern and colleagues describe an approach involving functionalized nanobodies which decrease the activity of voltage-gated Ca(2+) channels associated with β(1) subunits and promote their removal from the surface membrane of neurons and muscle.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734093/ https://www.ncbi.nlm.nih.gov/pubmed/36494383 http://dx.doi.org/10.1038/s41467-022-35027-5 |
| Sumario: | In this work, Morgenstern and colleagues describe an approach involving functionalized nanobodies which decrease the activity of voltage-gated Ca(2+) channels associated with β(1) subunits and promote their removal from the surface membrane of neurons and muscle. |
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