Cargando…

Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators

Eggerthella lenta is a prevalent human gut Actinobacterium implicated in drug, dietary phytochemical, and bile acid metabolism and associated with multiple human diseases. No genetic tools are currently available for the direct manipulation of E. lenta. Here, we construct shuttle vectors and develop...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Xueyang, Guthrie, Ben G. H., Alexander, Margaret, Noecker, Cecilia, Ramirez, Lorenzo, Glasser, Nathaniel R., Turnbaugh, Peter J., Balskus, Emily P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734109/
https://www.ncbi.nlm.nih.gov/pubmed/36494336
http://dx.doi.org/10.1038/s41467-022-33576-3