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Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators
Eggerthella lenta is a prevalent human gut Actinobacterium implicated in drug, dietary phytochemical, and bile acid metabolism and associated with multiple human diseases. No genetic tools are currently available for the direct manipulation of E. lenta. Here, we construct shuttle vectors and develop...
Autores principales: | Dong, Xueyang, Guthrie, Ben G. H., Alexander, Margaret, Noecker, Cecilia, Ramirez, Lorenzo, Glasser, Nathaniel R., Turnbaugh, Peter J., Balskus, Emily P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734109/ https://www.ncbi.nlm.nih.gov/pubmed/36494336 http://dx.doi.org/10.1038/s41467-022-33576-3 |
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