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Clonal diversity predicts persistence of SARS-CoV-2 epitope-specific T-cell response

T cells play a pivotal role in reducing disease severity during SARS-CoV-2 infection and formation of long-term immune memory. We studied 50 COVID-19 convalescent patients and found that T cell response was induced more frequently and persisted longer than circulating antibodies. We identified 756 c...

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Detalles Bibliográficos
Autores principales: Zornikova, Ksenia V., Khmelevskaya, Alexandra, Sheetikov, Savely A., Kiryukhin, Dmitry O., Shcherbakova, Olga V., Titov, Aleksei, Zvyagin, Ivan V., Efimov, Grigory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734123/
https://www.ncbi.nlm.nih.gov/pubmed/36494499
http://dx.doi.org/10.1038/s42003-022-04250-7