Visualizing the transiently populated closed-state of human HSP90 ATP binding domain

HSP90 are abundant molecular chaperones, assisting the folding of several hundred client proteins, including substrates involved in tumor growth or neurodegenerative diseases. A complex set of large ATP-driven structural changes occurs during HSP90 functional cycle. However, the existence of such st...

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Detalles Bibliográficos
Autores principales: Henot, Faustine, Rioual, Elisa, Favier, Adrien, Macek, Pavel, Crublet, Elodie, Josso, Pierre, Brutscher, Bernhard, Frech, Matthias, Gans, Pierre, Loison, Claire, Boisbouvier, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734131/
https://www.ncbi.nlm.nih.gov/pubmed/36494347
http://dx.doi.org/10.1038/s41467-022-35399-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734131/
https://www.ncbi.nlm.nih.gov/pubmed/36494347
http://dx.doi.org/10.1038/s41467-022-35399-8

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