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An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies

PURPOSE: Oncogene addiction provides important therapeutic opportunities for precision oncology treatment strategies. To date the cellular circuitries associated with driving oncoproteins, which eventually establish the phenotypic manifestation of oncogene addiction, remain largely unexplored. Data...

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書目詳細資料
Autores principales: Orlando, Eleonora, Medo, Matúš, Bensimon, Ariel, Quintin, Aurélie, Riedo, Rahel, Roth, Selina M., Riether, Carsten, Marti, Thomas M., Aebersold, Daniel M., Medová, Michaela, Aebersold, Ruedi, Zimmer, Yitzhak
格式: Online Artículo Texto
語言:English
出版: Springer International Publishing 2022
主題:
在線閱讀:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734221/
https://www.ncbi.nlm.nih.gov/pubmed/36494469
http://dx.doi.org/10.1007/s00018-022-04634-2