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An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies
PURPOSE: Oncogene addiction provides important therapeutic opportunities for precision oncology treatment strategies. To date the cellular circuitries associated with driving oncoproteins, which eventually establish the phenotypic manifestation of oncogene addiction, remain largely unexplored. Data...
Autores principales: | Orlando, Eleonora, Medo, Matúš, Bensimon, Ariel, Quintin, Aurélie, Riedo, Rahel, Roth, Selina M., Riether, Carsten, Marti, Thomas M., Aebersold, Daniel M., Medová, Michaela, Aebersold, Ruedi, Zimmer, Yitzhak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734221/ https://www.ncbi.nlm.nih.gov/pubmed/36494469 http://dx.doi.org/10.1007/s00018-022-04634-2 |
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