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An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies

PURPOSE: Oncogene addiction provides important therapeutic opportunities for precision oncology treatment strategies. To date the cellular circuitries associated with driving oncoproteins, which eventually establish the phenotypic manifestation of oncogene addiction, remain largely unexplored. Data...

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Detalles Bibliográficos
Autores principales: Orlando, Eleonora, Medo, Matúš, Bensimon, Ariel, Quintin, Aurélie, Riedo, Rahel, Roth, Selina M., Riether, Carsten, Marti, Thomas M., Aebersold, Daniel M., Medová, Michaela, Aebersold, Ruedi, Zimmer, Yitzhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734221/
https://www.ncbi.nlm.nih.gov/pubmed/36494469
http://dx.doi.org/10.1007/s00018-022-04634-2

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