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Impaired CD4(+) T cell recognition of SARS-CoV-2 variants of concern
We isolated CD4(+) T cell clones from healthcare workers infected with SARS-CoV-2 during the first COVID-19 wave and identified 21 epitopes across three viral proteins: spike, membrane and nucleoprotein. Focusing on spike protein, for seven of ten epitopes mutated in variants of concern, we found th...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734360/ https://www.ncbi.nlm.nih.gov/pubmed/36474117 http://dx.doi.org/10.1038/s41590-022-01353-5 |