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Angiotensin Type 2 Receptor Pharmacological Agonist Relieves Neurocognitive Deficits via Reducing Neuroinflammation and Microglial Engulfment of Dendritic Spines

Mechanically ventilated patients suffering critical illness are at high risk of developing neurocognitive impairments. Angiotensin type 2 receptor (AGTR2) has been demonstrated to be anti-inflammatory and neuroprotective. The present study thus aimed to investigate whether AGTR2 can alleviate cerebr...

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Detalles Bibliográficos
Autores principales: Shen, Liang, Chen, Dan-yang, Lou, Qian-qian, Cao, Peng, Hu, Rui, Jin, Yan, Wang, Di, Hu, Shan-shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734469/
https://www.ncbi.nlm.nih.gov/pubmed/36464726
http://dx.doi.org/10.1007/s11481-022-10054-7