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Potential protective effect of 3,3′-methylenebis(1-ethyl-4-hydroxyquinolin-2(1H)-one) against bleomycin-induced lung injury in male albino rat via modulation of Nrf2 pathway: biochemical, histological, and immunohistochemical study

Acute lung injury is a serious condition accounting for the majority of acute respiratory failure. Bleomycin (BLM) is an antibiotic that was first described as a chemotherapeutic agent. 3,3′-methylenebis(1-ethyl-4-hydroxyquinolin-2(1H)-one) was reported to have anti-inflammatory, anti-apoptotic, and...

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Detalles Bibliográficos
Autores principales: Hafez, Sara Mohamed Naguib Abdel, Saber, Entesar Ali, Aziz, Neven Makram, Kamel, Maha Yehia, Aly, Ashraf A., Abdelhafez, El-Shimaa M. N., Ibrahim, Manar Fouli Gaber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734634/
https://www.ncbi.nlm.nih.gov/pubmed/36480028
http://dx.doi.org/10.1007/s00210-022-02324-1