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Potential protective effect of 3,3′-methylenebis(1-ethyl-4-hydroxyquinolin-2(1H)-one) against bleomycin-induced lung injury in male albino rat via modulation of Nrf2 pathway: biochemical, histological, and immunohistochemical study
Acute lung injury is a serious condition accounting for the majority of acute respiratory failure. Bleomycin (BLM) is an antibiotic that was first described as a chemotherapeutic agent. 3,3′-methylenebis(1-ethyl-4-hydroxyquinolin-2(1H)-one) was reported to have anti-inflammatory, anti-apoptotic, and...
Autores principales: | Hafez, Sara Mohamed Naguib Abdel, Saber, Entesar Ali, Aziz, Neven Makram, Kamel, Maha Yehia, Aly, Ashraf A., Abdelhafez, El-Shimaa M. N., Ibrahim, Manar Fouli Gaber |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734634/ https://www.ncbi.nlm.nih.gov/pubmed/36480028 http://dx.doi.org/10.1007/s00210-022-02324-1 |
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