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Long-Term Adaptation to Galactose as a Sole Carbon Source Selects for Mutations Outside the Canonical GAL Pathway

Galactose is a secondary fermentable sugar that requires specific regulatory and structural genes for its assimilation, which are under catabolite repression by glucose. When glucose is absent, the catabolic repression is attenuated, and the structural GAL genes are fully activated. In Saccharomyces...

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Detalles Bibliográficos
Autores principales: Martínez, Artemiza A., Conboy, Andrew, Buskirk, Sean W., Marad, Daniel A., Lang, Gregory I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734637/
https://www.ncbi.nlm.nih.gov/pubmed/36482210
http://dx.doi.org/10.1007/s00239-022-10079-9