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ASK1-ER stress pathway-mediated fibrotic-EV release contributes to the interaction of alveolar epithelial cells and lung fibroblasts to promote mechanical ventilation-induced pulmonary fibrosis

Recent clinical research has revealed that mechanical ventilation (MV) can initiate pulmonary fibrosis and induce mechanical ventilation-induced pulmonary fibrosis (MVPF). However, the underlying mechanism remains largely uncharacterized. Based on a mouse model of MVPF and an alveolar epithelial cel...

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Detalles Bibliográficos
Autores principales: Tang, Ri, Mei, Shuya, Xu, Qiaoyi, Feng, Jinhua, Zhou, Yang, Xing, Shunpeng, He, Zhengyu, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734805/
https://www.ncbi.nlm.nih.gov/pubmed/36473935
http://dx.doi.org/10.1038/s12276-022-00901-1