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Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice

Obesity affects the function of multiple organs/tissues including the exocrine organ salivary glands. However, the effects of obesity on transcriptomes and cell compositions in the salivary glands have yet been studied by bulk RNA-sequencing and single-cell RNA-sequencing. Besides, the cell types in...

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Detalles Bibliográficos
Autores principales: Huang, Heping, Gao, Ce, Wang, Shuai, Wu, Fen, Wei, Jinsong, Peng, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735269/
https://www.ncbi.nlm.nih.gov/pubmed/36544475
http://dx.doi.org/10.1016/j.csbj.2022.11.054