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Forward Genetic Screens as Tools to Investigate Role and Mechanisms of EMT in Cancer

SIMPLE SUMMARY: Forward genetic screens link genome modifications to phenotypes, and have been successfully employed to identify oncogenes, tumor suppressor genes and genes involved in metastasis or therapy resistance. In particular, transposon-based insertional mutagenesis screens and CRISPR-based...

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Detalles Bibliográficos
Autores principales: Gasparics, Ákos, Sebe, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735433/
https://www.ncbi.nlm.nih.gov/pubmed/36497409
http://dx.doi.org/10.3390/cancers14235928