Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression

Recently, evidence has shown that GOT1 expression is upregulated in pancreatic cancer tissues and promotes cancer development, but the specific mechanism remains unclear. We found that GOT1 expression was upregulated in pancreatic cancer cell-derived exosomes. When PANC-1 cells were incubated with e...

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Detalles Bibliográficos
Autores principales: Guo, Yao, Chen, Taoyu, Liang, Xueyi, Gou, Shanmiao, Xiong, Jiongxin, Cui, Jing, Peng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735520/
https://www.ncbi.nlm.nih.gov/pubmed/36497150
http://dx.doi.org/10.3390/cells11233893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735520/
https://www.ncbi.nlm.nih.gov/pubmed/36497150
http://dx.doi.org/10.3390/cells11233893

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