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Comparative Efficiency of Gene-Activated Matrices Based on Chitosan Hydrogel and PRP Impregnated with BMP2 Polyplexes for Bone Regeneration

Gene therapy is one of the most promising approaches in regenerative medicine. Gene-activated matrices provide stable gene expression and the production of osteogenic proteins in situ to stimulate osteogenesis and bone repair. In this study, we developed new gene-activated matrices based on polylact...

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Detalles Bibliográficos
Autores principales: Nedorubova, Irina Alekseevna, Bukharova, Tatiana Borisovna, Mokrousova, Viktoria Olegovna, Khvorostina, Maria Aleksandrovna, Vasilyev, Andrey Vyacheslavovich, Nedorubov, Andrey Anatolevich, Grigoriev, Timofei Evgenevich, Zagoskin, Yuriy Dmitrievich, Chvalun, Sergei Nicolaevich, Kutsev, Sergey Ivanovich, Goldshtein, Dmitry Vadimovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735524/
https://www.ncbi.nlm.nih.gov/pubmed/36499056
http://dx.doi.org/10.3390/ijms232314720