Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds

The obligate intracellular bacterium Chlamydia trachomatis is the major causative agent of bacterial sexually transmitted diseases worldwide. In infected cells, the ceramide transport protein (CERT) is recruited to inclusions, where C. trachomatis replicates using host-synthesized ceramide. The cera...

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Detalles Bibliográficos
Autores principales: Kumagai, Keigo, Sakai, Shota, Ueno, Masaharu, Kataoka, Michiyo, Kobayashi, Shu, Hanada, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735676/
https://www.ncbi.nlm.nih.gov/pubmed/36499025
http://dx.doi.org/10.3390/ijms232314697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735676/
https://www.ncbi.nlm.nih.gov/pubmed/36499025
http://dx.doi.org/10.3390/ijms232314697

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