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Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds
The obligate intracellular bacterium Chlamydia trachomatis is the major causative agent of bacterial sexually transmitted diseases worldwide. In infected cells, the ceramide transport protein (CERT) is recruited to inclusions, where C. trachomatis replicates using host-synthesized ceramide. The cera...
Autores principales: | Kumagai, Keigo, Sakai, Shota, Ueno, Masaharu, Kataoka, Michiyo, Kobayashi, Shu, Hanada, Kentaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735676/ https://www.ncbi.nlm.nih.gov/pubmed/36499025 http://dx.doi.org/10.3390/ijms232314697 |
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