PKCβ Facilitates Leukemogenesis in Chronic Lymphocytic Leukaemia by Promoting Constitutive BCR-Mediated Signalling

SIMPLE SUMMARY: Chronic lymphocytic leukaemia (CLL) is the most common blood cancer in the Western world and remains incurable. While a cause for this cancer has not been defined, one specific protein, protein kinase CβII (PKCβII), is highly expressed in CLL cells and is linked with a poorer clinica...

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Detalles Bibliográficos
Autores principales: Hay, Jodie, Tarafdar, Anuradha, Holroyd, Ailsa K., Moka, Hothri A., Dunn, Karen M., Alshayeb, Alzahra, Lloyd, Bryony H., Cassels, Jennifer, Malik, Natasha, Khan, Ashfia F., Sou, IengFong, Lees, Jamie, Almuhanna, Hassan N. B., Kalakonda, Nagesh, Slupsky, Joseph R., Michie, Alison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735720/
https://www.ncbi.nlm.nih.gov/pubmed/36497487
http://dx.doi.org/10.3390/cancers14236006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735720/
https://www.ncbi.nlm.nih.gov/pubmed/36497487
http://dx.doi.org/10.3390/cancers14236006

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