TIMP3 Gene Polymorphisms of -1296 T > C and -915 A > G Increase the Susceptibility to Arsenic-Induced Skin Cancer: A Cohort Study and In Silico Analysis of Mutation Impacts

Long-term exposure to arsenic may induce several human cancers, including non-melanoma skin cancer. The tissue inhibitor of metalloproteinase (TIMP)-3, encoded by the TIMP3 gene, may inhibit tumor growth, invasion, and metastasis of several cancer types. In this study, we aimed to investigate effect...

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Detalles Bibliográficos
Autores principales: Wu, Meei-Maan, Chen, Chi-Wei, Chen, Chiu-Yi, Lee, Chih-Hung, Chou, Mark, Hsu, Ling-I, Lee, Te-Chang, Chen, Chien-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735753/
https://www.ncbi.nlm.nih.gov/pubmed/36499314
http://dx.doi.org/10.3390/ijms232314980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735753/
https://www.ncbi.nlm.nih.gov/pubmed/36499314
http://dx.doi.org/10.3390/ijms232314980

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