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TIMP3 Gene Polymorphisms of -1296 T > C and -915 A > G Increase the Susceptibility to Arsenic-Induced Skin Cancer: A Cohort Study and In Silico Analysis of Mutation Impacts
Long-term exposure to arsenic may induce several human cancers, including non-melanoma skin cancer. The tissue inhibitor of metalloproteinase (TIMP)-3, encoded by the TIMP3 gene, may inhibit tumor growth, invasion, and metastasis of several cancer types. In this study, we aimed to investigate effect...
Autores principales: | Wu, Meei-Maan, Chen, Chi-Wei, Chen, Chiu-Yi, Lee, Chih-Hung, Chou, Mark, Hsu, Ling-I, Lee, Te-Chang, Chen, Chien-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735753/ https://www.ncbi.nlm.nih.gov/pubmed/36499314 http://dx.doi.org/10.3390/ijms232314980 |
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