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Targeting Menin and CD47 to Address Unmet Needs in Acute Myeloid Leukemia

SIMPLE SUMMARY: Despite recent, rapid drug development success for patients with acute myeloid leukemia, distinct molecular and genetic aberrations still confer a poor prognosis. In this review, we explore the preclinical and early clinical development of two promising approaches: disrupting menin s...

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Detalles Bibliográficos
Autores principales: Matthews, Andrew H., Pratz, Keith W., Carroll, Martin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735817/
https://www.ncbi.nlm.nih.gov/pubmed/36497385
http://dx.doi.org/10.3390/cancers14235906