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The Role of 8-oxoG Repair Systems in Tumorigenesis and Cancer Therapy

Tumorigenesis is highly correlated with the accumulation of mutations. The abundant and extensive DNA oxidation product, 8-Oxoguanine (8-oxoG), can cause mutations if it is not repaired by 8-oxoG repair systems. Therefore, the accumulation of 8-oxoG plays an essential role in tumorigenesis. To avoid...

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Detalles Bibliográficos
Autores principales: Li, Chunshuang, Xue, Yaoyao, Ba, Xueqing, Wang, Ruoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735852/
https://www.ncbi.nlm.nih.gov/pubmed/36497058
http://dx.doi.org/10.3390/cells11233798