Synthesis of 1,5-Substituted Pyrrolidin-2-ones from Donor–Acceptor Cyclopropanes and Anilines/Benzylamines

We developed a straightforward synthetic route to pharmacologically important 1,5-substituted pyrrolidin-2-ones from donor–acceptor cyclopropanes bearing an ester group as one of the acceptor substituents. This method includes a Lewis acid-catalyzed opening of the donor–acceptor cyclopropane with pr...

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Detalles Bibliográficos
Autores principales: Boichenko, Maksim A., Plodukhin, Andrey Yu., Shorokhov, Vitaly V., Lebedev, Danyla S., Filippova, Anastasya V., Zhokhov, Sergey S., Tarasenko, Elena A., Rybakov, Victor B., Trushkov, Igor V., Ivanova, Olga A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735934/
https://www.ncbi.nlm.nih.gov/pubmed/36500574
http://dx.doi.org/10.3390/molecules27238468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735934/
https://www.ncbi.nlm.nih.gov/pubmed/36500574
http://dx.doi.org/10.3390/molecules27238468

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