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Nrf2 Deficiency Exacerbated CLP-Induced Pulmonary Injury and Inflammation through Autophagy- and NF-κB/PPARγ-Mediated Macrophage Polarization

The balance between M1 and M2 macrophage polarization is involved in the regulation of pulmonary inflammation. Nuclear factor erythroid-derived 2-like 2 (Nfe2l2, also known as Nrf2), a nuclear transcription factor, is reported to play protective roles in acute lung injury (ALI) and inflammation, and...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Wang, Jin, Zhang, Jing, Sang, Aming, Ye, Xujun, Cheng, Zhenshun, Li, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735993/
https://www.ncbi.nlm.nih.gov/pubmed/36497185
http://dx.doi.org/10.3390/cells11233927