Fluorinated and Non-Fluorinated 1,4-Diarylpyrazoles via MnO(2)-Mediated Mechanochemical Deacylative Oxidation of 5-Acylpyrazolines †

A solvent-free two-step synthesis of polyfunctionalized pyrazoles under ball-milling mechanochemical conditions was developed. The protocol comprises (3 + 2)-cycloaddition of in situ generated nitrile imines and chalcones, followed by oxidation of the initially formed 5-acylpyrazolines with activate...

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Detalles Bibliográficos
Autores principales: Utecht-Jarzyńska, Greta, Kowalczyk, Anna, Jasiński, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736116/
https://www.ncbi.nlm.nih.gov/pubmed/36500541
http://dx.doi.org/10.3390/molecules27238446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736116/
https://www.ncbi.nlm.nih.gov/pubmed/36500541
http://dx.doi.org/10.3390/molecules27238446

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