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Inhibitory Effects of Nobiletin on Voltage-Gated Na(+) Channel in Rat Ventricular Myocytes Based on Electrophysiological Analysis and Molecular Docking Method

Nobiletin (NOB) has attracted much attention owing to its outstanding bioactivities. This study aimed to investigate its anti-arrhythmic effect through electrophysiological and molecular docking studies. We assessed the anti-arrhythmic effects of NOB using aconitine-induced ventricular arrhythmia in...

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Detalles Bibliográficos
Autores principales: Gu, Youwei, Wang, Jieru, Li, Mengting, Zhong, Fei, Xiang, Jie, Xu, Zhengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736168/
https://www.ncbi.nlm.nih.gov/pubmed/36499507
http://dx.doi.org/10.3390/ijms232315175