PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[(18)F]fluoro-6-deoxy-D-fructose

Fluorine-18 labeled 6-fluoro-6-deoxy-D-fructose (6-[(18)F]FDF) targets the fructose-preferred facilitative hexose transporter GLUT5, which is expressed predominantly in brain microglia and activated in response to inflammatory stimuli. We hypothesize that 6-[(18)F]FDF will specifically image microgl...

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Detalles Bibliográficos
Autores principales: Boyle, Amanda J., Murrell, Emily, Tong, Junchao, Schifani, Christin, Narvaez, Andrea, Wuest, Melinda, West, Frederick, Wuest, Frank, Vasdev, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736258/
https://www.ncbi.nlm.nih.gov/pubmed/36500626
http://dx.doi.org/10.3390/molecules27238529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736258/
https://www.ncbi.nlm.nih.gov/pubmed/36500626
http://dx.doi.org/10.3390/molecules27238529

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