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Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues

SIMPLE SUMMARY: Our study investigates the well-known observation/quandary that cancer occurs more frequently in men while autoimmune diseases (AIDs) occur more frequently in women. This has motivated us to explore whether these sex biases may have a common basis. To study that, we assembled and ana...

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Detalles Bibliográficos
Autores principales: Crawford, David R., Sinha, Sanju, Nair, Nishanth Ulhas, Ryan, Bríd M., Barnholtz-Sloan, Jill S., Mount, Stephen M., Erez, Ayelet, Aldape, Kenneth, Castle, Philip E., Rajagopal, Padma S., Day, Chi-Ping, Schäffer, Alejandro A., Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736300/
https://www.ncbi.nlm.nih.gov/pubmed/36497367
http://dx.doi.org/10.3390/cancers14235885