Insights into Network of Hot Spots of Aggregation in Nucleophosmin 1

In a protein, point mutations associated with diseases can alter the native structure and provide loss or alteration of functional levels, and an internal structural network defines the connectivity among domains, as well as aggregate/soluble states’ equilibria. Nucleophosmin (NPM)1 is an abundant n...

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Detalles Bibliográficos
Autores principales: Florio, Daniele, La Manna, Sara, Di Natale, Concetta, Leone, Marilisa, Mercurio, Flavia Anna, Napolitano, Fabiana, Malfitano, Anna Maria, Marasco, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736328/
https://www.ncbi.nlm.nih.gov/pubmed/36499032
http://dx.doi.org/10.3390/ijms232314704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736328/
https://www.ncbi.nlm.nih.gov/pubmed/36499032
http://dx.doi.org/10.3390/ijms232314704

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