Development of a SPE-LC-MS Method for the Quantitation of Palbociclib and Abemaciclib in Human Plasma

Palbociclib and abemaciclib are two cyclin-dependent kinases 4 and 6 used for breast cancer treatment. Levels of these medicines present a significant interindividual variability, so monitoring those concentrations might be necessary in therapy. Most of the methods presented so far in the literature...

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Detalles Bibliográficos
Autores principales: Calucică, Daniela Maria, Manda, Costel-Valentin, Găman, Amelia Maria, Răileanu, Ștefan, Stanca, Liliana, Popescu, Monica Denisa Elena, Mateescu, Olivia Garofița, Biță, Andrei, Croitoru, Octavian, Neamțu, Simona-Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736392/
https://www.ncbi.nlm.nih.gov/pubmed/36500697
http://dx.doi.org/10.3390/molecules27238604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736392/
https://www.ncbi.nlm.nih.gov/pubmed/36500697
http://dx.doi.org/10.3390/molecules27238604

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