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Retroviral Replicating Vector Toca 511 (Vocimagene Amiretrorepvec) for Prodrug Activator Gene Therapy of Lung Cancer

SIMPLE SUMMARY: A unique gene therapy strategy based on tumor-selectively replicating retroviral vectors has shown promising results in clinical trials for glioma and gastrointestinal cancers. Here, we applied this strategy to the treatment of lung cancer, the leading cause of cancer deaths worldwid...

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Detalles Bibliográficos
Autores principales: Kushiya, Hiroki, Hiraoka, Kei, Suzuki, Tomohiro, Inoko, Kazuho, Inagaki, Akihito, Niwa, Hiroki, Sasaki, Katsunori, Nakamura, Toru, Tsuchikawa, Takahiro, Shichinohe, Toshiaki, Jolly, Douglas J., Kasahara, Noriyuki, Hirano, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736610/
https://www.ncbi.nlm.nih.gov/pubmed/36497300
http://dx.doi.org/10.3390/cancers14235820