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Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation

Our previous study demonstrated that ovarian wild-type P53-induced phosphatase 1 (WIP1) expression decreased with age. We hypothesized that WIP1 activity was related to ovarian aging. The role of WIP1 in regulating ovarian aging and its mechanisms remain to be elucidated. Adult female mice with or w...

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Detalles Bibliográficos
Autores principales: Zhou, Su, Xi, Yueyue, Chen, Yingying, Fu, Fangfang, Yan, Wei, Li, Milu, Wu, Yaling, Luo, Aiyue, Li, Ya, Wang, Shixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736686/
https://www.ncbi.nlm.nih.gov/pubmed/36497179
http://dx.doi.org/10.3390/cells11233920