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Development of Hydroxamate Derivatives Containing a Pyrazoline Moiety as APN Inhibitors to Overcome Angiogenesis
Aminopeptidase N (APN) was closely associated with cancer invasion, metastasis, and angiogenesis. Therefore, APN inhibitors have attracted more and more attention of scientists as antitumor agents. In the current study, we designed, synthesized, and evaluated one new series of pyrazoline-based hydro...
Autores principales: | Liu, Yangyang, Zhao, Dongsheng, Zhang, Chenghua, Fang, Hui, Shen, Qingsitong, Wang, Zhixian, Cao, Jiangying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736874/ https://www.ncbi.nlm.nih.gov/pubmed/36500432 http://dx.doi.org/10.3390/molecules27238339 |
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