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Identification of Agents That Ameliorate Hyperphosphatemia-Suppressed Myogenin Expression Involved in the Nrf2/p62 Pathway in C2C12 Skeletal Muscle Cells

Hyperphosphatemia can occur as a result of reduced phosphate (P(i)) excretion in cases of kidney dysfunction, which can induce muscle wasting and suppress myogenic differentiation. Higher P(i) suppresses myogenic differentiation and promotes muscle atrophy through canonical (oxidative stress-mediate...

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Detalles Bibliográficos
Autores principales: Hsieh Li, Shu-Man, Liu, Shu-Ting, Chang, Yung-Lung, Chen, Gunng-Shinng, Huang, Shih-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736935/
https://www.ncbi.nlm.nih.gov/pubmed/36499650
http://dx.doi.org/10.3390/ijms232315324