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Identification of Agents That Ameliorate Hyperphosphatemia-Suppressed Myogenin Expression Involved in the Nrf2/p62 Pathway in C2C12 Skeletal Muscle Cells
Hyperphosphatemia can occur as a result of reduced phosphate (P(i)) excretion in cases of kidney dysfunction, which can induce muscle wasting and suppress myogenic differentiation. Higher P(i) suppresses myogenic differentiation and promotes muscle atrophy through canonical (oxidative stress-mediate...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736935/ https://www.ncbi.nlm.nih.gov/pubmed/36499650 http://dx.doi.org/10.3390/ijms232315324 |