NSCLC Cells Resistance to PI3K/mTOR Inhibitors Is Mediated by Delta-6 Fatty Acid Desaturase (FADS2)

Hyperactivation of the phosphatidylinositol-3-kinase (PI3K) pathway is one of the most common events in human cancers. Several efforts have been made toward the identification of selective PI3K pathway inhibitors. However, the success of these molecules has been partially limited due to unexpected t...

Descripción completa

Detalles Bibliográficos
Autores principales: Colombo, Marika, Passarelli, Federico, Corsetto, Paola A., Rizzo, Angela M., Marabese, Mirko, De Simone, Giulia, Pastorelli, Roberta, Broggini, Massimo, Brunelli, Laura, Caiola, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736998/
https://www.ncbi.nlm.nih.gov/pubmed/36496978
http://dx.doi.org/10.3390/cells11233719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736998/
https://www.ncbi.nlm.nih.gov/pubmed/36496978
http://dx.doi.org/10.3390/cells11233719

Ejemplares similares