Lewis Acid-Catalyzed 2,3-Dihydrofuran Acetal Ring-Opening Benzannulations toward Functionalized 1-Hydroxycarbazoles

The development of a Lewis acid-catalyzed, intramolecular ring-opening benzannulation of 5-(indolyl)2,3-dihydrofuran acetals is described. The resulting 1-hydroxycarbazole-2-carboxylates are formed in up to 90% yield in 1 h. The dihydrofuran acetals are readily accessed from the reactions of enol et...

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Detalles Bibliográficos
Autores principales: Yuan, Shaoren, Guerra Faura, Gabriel, Areheart, Hailey E., Peulen, Natalie E., France, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737012/
https://www.ncbi.nlm.nih.gov/pubmed/36500437
http://dx.doi.org/10.3390/molecules27238344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737012/
https://www.ncbi.nlm.nih.gov/pubmed/36500437
http://dx.doi.org/10.3390/molecules27238344

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