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Lewis Acid-Catalyzed 2,3-Dihydrofuran Acetal Ring-Opening Benzannulations toward Functionalized 1-Hydroxycarbazoles

The development of a Lewis acid-catalyzed, intramolecular ring-opening benzannulation of 5-(indolyl)2,3-dihydrofuran acetals is described. The resulting 1-hydroxycarbazole-2-carboxylates are formed in up to 90% yield in 1 h. The dihydrofuran acetals are readily accessed from the reactions of enol et...

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Detalles Bibliográficos
Autores principales:	Yuan, Shaoren, Guerra Faura, Gabriel, Areheart, Hailey E., Peulen, Natalie E., France, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737012/ https://www.ncbi.nlm.nih.gov/pubmed/36500437 http://dx.doi.org/10.3390/molecules27238344

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