Targeting FTO Suppresses Pancreatic Carcinogenesis via Regulating Stem Cell Maintenance and EMT Pathway

SIMPLE SUMMARY: Current treatment strategies for pancreatic cancer (PC) yield poor survival outcomes. It is thus essential to identify factors that orchestrate pancreatic tumorigenesis and contribute to therapeutic resistance. Fat mass and obesity-associated protein (FTO) play a crucial role in deme...

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Detalles Bibliográficos
Autores principales: Garg, Rachana, Melstrom, Laleh, Chen, Jianjun, He, Chuan, Goel, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737034/
https://www.ncbi.nlm.nih.gov/pubmed/36497402
http://dx.doi.org/10.3390/cancers14235919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737034/
https://www.ncbi.nlm.nih.gov/pubmed/36497402
http://dx.doi.org/10.3390/cancers14235919

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