Natural Compound 2,2′,4′-Trihydroxychalcone Suppresses T Helper 17 Cell Differentiation and Disease Progression by Inhibiting Retinoid-Related Orphan Receptor Gamma T

Retinoid-related orphan receptor γt (RORγt), a vital transcription factor for the differentiation of the pro-inflammatory Th17 cells, is essential to the inflammatory response and pathological process mediated by Th17 cells. Pharmacological inhibition of the nuclear receptor RORγt provides novel imm...

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Detalles Bibliográficos
Autores principales: Yang, Yana, Qi, Wenhui, Zhang, Yanyan, Wang, Ruining, Bao, Mingyue, Tian, Mengyuan, Li, Xing, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737070/
https://www.ncbi.nlm.nih.gov/pubmed/36498875
http://dx.doi.org/10.3390/ijms232314547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737070/
https://www.ncbi.nlm.nih.gov/pubmed/36498875
http://dx.doi.org/10.3390/ijms232314547

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