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Effects of Molecular Crowding and Betaine on HSPB5 Interactions, with Target Proteins Differing in the Quaternary Structure and Aggregation Mechanism

The aggregation of intracellular proteins may be enhanced under stress. The expression of heat-shock proteins (HSPs) and the accumulation of osmolytes are among the cellular protective mechanisms in these conditions. In addition, one should remember that the cell environment is highly crowded. The a...

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Detalles Bibliográficos
Autores principales: Borzova, Vera A., Roman, Svetlana G., Pivovarova, Anastasiya V., Chebotareva, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737104/
https://www.ncbi.nlm.nih.gov/pubmed/36499725
http://dx.doi.org/10.3390/ijms232315392