The Mitochondrial Protein MitoNEET as a Probe for the Allostery of Glutamate Dehydrogenase

The proteins glutamate dehydrogenase (GDH) and mitoNEET are both targets of drug development efforts to treat metabolic disorders, cancer, and neurodegenerative diseases. However, these two proteins differ starkly in the current knowledge about ligand binding sites. MitoNEET is a [2Fe-2S]-containing...

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Detalles Bibliográficos
Autores principales: Nnatubeugo, Chimere, Johnson, Erica, Gisondi, Sarah, Roland, Felicia, Geldenhuys, Werner J., Menze, Michael A., Konkle, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737137/
https://www.ncbi.nlm.nih.gov/pubmed/36500407
http://dx.doi.org/10.3390/molecules27238314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737137/
https://www.ncbi.nlm.nih.gov/pubmed/36500407
http://dx.doi.org/10.3390/molecules27238314

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