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The Mitochondrial Protein MitoNEET as a Probe for the Allostery of Glutamate Dehydrogenase
The proteins glutamate dehydrogenase (GDH) and mitoNEET are both targets of drug development efforts to treat metabolic disorders, cancer, and neurodegenerative diseases. However, these two proteins differ starkly in the current knowledge about ligand binding sites. MitoNEET is a [2Fe-2S]-containing...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737137/ https://www.ncbi.nlm.nih.gov/pubmed/36500407 http://dx.doi.org/10.3390/molecules27238314 |