Hepatic Oleate Regulates Insulin-like Growth Factor-Binding Protein 1 Partially through the mTORC1-FGF21 Axis during High-Carbohydrate Feeding

Stearoyl-CoA desaturase-1 (SCD1) catalyzes the rate-liming step of monounsaturated fatty acid biosynthesis and is a key regulator of systemic glucose metabolism. Mice harboring either a global (GKO) or liver-specific deletion (LKO) of Scd1 display enhanced insulin signaling and whole-body glucose up...

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Detalles Bibliográficos
Autores principales: O’Neill, Lucas M., Phang, Yar Xin, Liu, Zhaojin, Lewis, Sarah A., Aljohani, Ahmed, McGahee, Ayren, Wade, Gina, Kalyesubula, Mugagga, Simcox, Judith, Ntambi, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737156/
https://www.ncbi.nlm.nih.gov/pubmed/36498997
http://dx.doi.org/10.3390/ijms232314671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737156/
https://www.ncbi.nlm.nih.gov/pubmed/36498997
http://dx.doi.org/10.3390/ijms232314671

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