Green and Efficient Construction of Chromeno[3,4-c]pyrrole Core via Barton–Zard Reaction from 3-Nitro-2H-chromenes and Ethyl Isocyanoacetate

A regioselective one-pot method for the synthesis of 1-ethyl 2,4-dihydrochromene[3,4-c]pyrroles in 63–94% yields from available 2-phenyl-, 2-trifluoro(trichloro)methyl- or 2-phenyl-2-(trifluoromethyl)-3-nitro-2H-chromenes and ethyl isocyanoacetate through the Barton–Zard reaction in ethanol at reflu...

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Detalles Bibliográficos
Autores principales: Kochnev, Ivan A., Barkov, Alexey Y., Zimnitskiy, Nikolay S., Korotaev, Vladislav Y., Sosnovskikh, Vyacheslav Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737169/
https://www.ncbi.nlm.nih.gov/pubmed/36500555
http://dx.doi.org/10.3390/molecules27238456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737169/
https://www.ncbi.nlm.nih.gov/pubmed/36500555
http://dx.doi.org/10.3390/molecules27238456

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